Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12673157 | 0.92 | CASP2 (0.61) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL840681 | 0.92 | — | — | |
| SCHEMBL16072836 | 0.90 | CASP2 (0.59) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL12583601 | 0.90 | CASP2 (0.59) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14576993 | 0.89 | CASP2 (0.78) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7537764 | 0.89 | CASP2 (0.86) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9921430 | 0.88 | CASP2 (0.57) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9921440 | 0.88 | CASP2 (0.57) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9921437 | 0.88 | CASP2 (0.57) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27266338 | 0.88 | CASP2 (0.57) | CASP2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-08-07 | — | — | US | disclosed |
| US-10010589-B2 | — | — | 2018-07-03 | — | — | US | disclosed |
| US-9145514-B2 | Temperature management indicator and structure having the same attached | NICHIYU GIKEN KOGYO CO., LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| EP-2554961-A1 | TEMPERATURE MANAGEMENT INDICATOR AND STRUCTURE HAVING THE SAME ATTACHED | Nichiyu Giken Kogyo Co. Ltd. (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-20130014690-A1 | TEMPERATURE MANAGEMENT INDICATOR AND STRUCTURE HAVING THE SAME ATTACHED | NICHIYU GIKEN KOGYO CO., LTD. (JP) | 2013-01-17 | — | — | US | disclosed |
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-04-26 | — | — | US | disclosed |
| US-7179872-B2 | Chain transfer agents for RAFT polymerization in aqueous media | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2007-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010589-B2 | — | TYMP, MTAP, TUBB6 | CASP2 537/4885HDAC3 2701/4885HDAC1 1700/4885 |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | SGMS1, SGMS2, PHOSPHO1 | CASP2 472/4885HDAC3 2423/4885HDAC1 1443/4885 |
| US-20120100555-A1 | Synthesis And Use Of Fluorophore-Tagged Antimalarials | ABCC1, DHFR, GFPT1 | CASP2 969/4885HDAC3 1663/4885HDAC1 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.