SCHEMBL22483189

SCHEMBL22483189

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc5c6c7ccccc7c7ccccc7c6n(-c6ccccc6)c5c4)n3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A P37288 1/20 0.39
▸ MEN1 O00255 5/20 0.36
▸ KMT2A Q03164 5/20 0.36
▸ MAPT P10636 2/20 0.36
▸ HSP90AA1 P07900 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.35
▸ HPGD P15428 1/20 0.35
▸ ABCG2 Q9UNQ0 1/20 0.35
▸ GAA P10253 1/20 0.34
▸ ATM Q13315 2/20 0.34
▸ MAT2A P31153 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ PRMT5 O14744 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16302992 0.96 ATM (0.38) AVPR1AMEN1KMT2AMAPTHSP90AA1
SCHEMBL27352598 0.95 AVPR1A (0.36) AVPR1AMEN1KMT2AMAPTHSP90AA1
SCHEMBL22097203 0.90 L3MBTL1 (0.41) AVPR1AMEN1KMT2AMAPTHSP90AA1
SCHEMBL2627491 0.90 AVPR1A (0.35) AVPR1AMEN1KMT2AMAPTHSP90AA1
SCHEMBL22097262 0.90 L3MBTL1 (0.41) AVPR1AMEN1KMT2AMAPTHSP90AA1
SCHEMBL28561095 0.90 ATM (0.37) AVPR1AMEN1KMT2AMAPTALDH1A1
SCHEMBL22097074 0.88 L3MBTL1 (0.42) AVPR1AMEN1KMT2AMAPTALDH1A1
SCHEMBL22097075 0.88 L3MBTL1 (0.42) AVPR1AMEN1KMT2AMAPTALDH1A1
SCHEMBL18667615 0.86 L3MBTL1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22483153 0.86 MAOB (0.38) AVPR1AMEN1KMT2AMAPTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 — — US disclosed
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 — — US disclosed
US-20230209856-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 — — US disclosed
US-20230209856-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 — — US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 — — US disclosed
US-20230200102-A1 MIXED LAYER, METHOD OF PREPARING THE MIXED LAYER, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 — — US disclosed
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, LEF1 AVPR1A 3268/4885MEN1 700/4885KMT2A 1690/4885
US-11760769-B2 Composition and organic light-emitting device including the same CRY1, CRY2, LEF1 AVPR1A 3268/4885MEN1 700/4885KMT2A 1690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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