Indole

Indole

SCHEMBL224834

C=CC(=O)O.c1ccc2[nH]ccc2c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.63
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
ITGB2 P05107 1/20 0.63
ICAM1 P05362 1/20 0.63
ITGAL P20701 1/20 0.63
CA4 P22748 1/20 0.63
CA6 P23280 1/20 0.63
AHR P35869 1/20 0.63
ADK P55263 1/20 0.63
KDM4E B2RXH2 3/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 2/20 0.44
ENPP2 Q13822 1/20 0.44
CTNNB1 P35222 1/20 0.44
WNT3A P56704 1/20 0.44
MAPT P10636 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL29966814 1.00 TRPA1 (0.63) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL27639366 0.98 TRPA1 (0.61) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL29127707 0.89 TRPA1 (0.63) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL7593945 0.87 TRPA1 (0.61) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL7634666 0.87 TRPA1 (0.65) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL29504142 0.87 TRPA1 (0.65) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL7634660 0.87 TRPA1 (0.65) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL4752595 0.87 TRPA1 (0.65) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL27448469 0.87 TRPA1 (0.65) TRPA1CA1CA2ITGB2ICAM1
Indole SCHEMBL28479409 0.86 TRPA1 (0.77) TRPA1CA1CA2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1023 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders UNIV IOWA RES FOUND (US) 2026-02-26 US claimed
CN-118937534-A Fecal biomarker for yin deficiency syndrome of Alzheimer disease and application thereof 辽宁中医药大学 2024-11-12 CN claimed
CN-118562664-A Lactobacillus mucosae capable of relieving colorectal cancer related to ulcerative colitis and application thereof 江南大学 2024-08-30 CN claimed
CN-118566487-A Device for diagnosing gastric cancer and device for predicting prognosis of gastric cancer patient 清华大学 2024-08-30 CN claimed
CN-118091146-A Neurodegenerative disease marker based on blood metabolites and application thereof 中国科学院深圳先进技术研究院 2024-05-28 CN claimed
CN-117915926-A Serometabonomics associated with Chimeric Antigen Receptor (CAR) T cell therapy 得克萨斯州大学系统董事会 2024-04-19 CN claimed
US-20240010693-A1 PEPTIDES FROM HUMAN B-CASEIN THAT HAVE ANTI-BACTERIAL ACTIVITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-01-11 US claimed
EP-4243853-A2 PEPTIDES FROM HUMAN B-CASEIN THAT HAVE ANTI-BACTERIAL ACTIVITY The Regents of the University of California (US) 2023-09-20 EP claimed
WO-2023066132-A1 STARCH-INDOLE ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 山东善维免疫科技有限公司 2023-04-27 WO claimed
CN-115175575-A Engineered bacterial compositions and uses thereof 赛里斯治疗公司 2022-10-11 CN claimed
CN-1239548-A Method for detecting or determining viruses TONEN CORP (JP) 1999-12-22 CN claimed
CN-1230994-A Deformylation of f-MET peptides in bacterial expression system MONSANTO CO (US) 1999-10-06 CN claimed
EP-0917580-A1 DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS MONSANTO COMPANY (US) 1999-05-26 EP claimed
US-5834243-A DEFORMYLATING RECOMBINANT PROTEIN IN A BACTERIAL HOST CELL MONSANTO TECHNOLOGY LLC 1998-11-10 US claimed
WO-1998003664-A1 DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS MONSANTO COMPANY (US) 1998-01-29 WO claimed
US-5366876-A PLASMID FOR THE EXPRESSION OF HORMONE IN ESCHERICHIA LUCKY LTD. (KR) 1994-11-22 US claimed
US-5270180-A Method for the production of salmon growth hormone using a synthetic gene LUCKY, LTD. (KR) 1993-12-14 US claimed
EP-0215388-B1 PLASMID VECTOR AND A METHOD FOR REGULATION OF GENE EXPRESSION USING THE SAME AJINOMOTO CO., INC. (JP) 1991-12-04 EP claimed
EP-0215388-A1 Plasmid vector and a method for regulation of gene expression using the same AJINOMOTO CO., INC. (JP) 1987-03-25 EP claimed
EP-0180192-A1 Novel plasmids RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1986-05-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053887-A1 Methods and Kits to Prevent And/Or Treat Cardiac Disorders KYNU, AADAT, TPH1 TRPA1 1052/4885CA1 2837/4885CA2 2711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.