Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DPYD | Q12882 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410887 | 0.81 | ALDH1A1 (0.35) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL11708542 | 0.77 | KMT2A (0.68) | KMT2AKDM4EGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL3571705 | 0.76 | KMT2A (0.51) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4564516 | 0.75 | GRIA1 (0.49) | KMT2AALDH1A1GAAMEN1TDP1 | |
| SCHEMBL148953 | 0.75 | CYP3A4 (0.37) | KMT2AKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17791229 | 0.75 | CYP1A2 (0.49) | KMT2AKDM4ESMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9021896 | 0.75 | TK1 (0.56) | HPGD | |
| SCHEMBL3562882 | 0.74 | KMT2A (0.49) | KMT2AGAASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL12410891 | 0.73 | TK1 (0.41) | KMT2AKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL17243367 | 0.73 | KMT2A (0.36) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191488-A1 | Method for the treatment of a ubiquitin conjugating disorder | BANERJEE AMIT | 2007-08-16 | — | — | US | claimed |
| EP-1778011-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS | Hygeia Biological Systems (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020681-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS | HYGEIA BIOLOGICAL SYSTEMS (US) | 2006-02-23 | — | — | WO | claimed |
| US-20060035890-A1 | Compounds and methods for the treatment of ubiquitin conjugating disorders | AMIT BANERJEE | 2006-02-16 | — | — | US | claimed |
| CN-108341960-B | Dynamic polymer containing combined dynamic covalent bonds and application thereof | 厦门天策材料科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| US-8003572-B2 | Method for the treatment of a ubiquitin conjugating disorder | Banerjee, Amit (US) | 2011-08-23 | — | — | US | disclosed |
| US-20070191488-A1 | Method for the treatment of a ubiquitin conjugating disorder | BANERJEE AMIT | 2007-08-16 | — | — | US | disclosed |
| EP-1778011-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS | Hygeia Biological Systems (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020681-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS | HYGEIA BIOLOGICAL SYSTEMS (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060035890-A1 | Compounds and methods for the treatment of ubiquitin conjugating disorders | AMIT BANERJEE | 2006-02-16 | — | — | US | disclosed |