SCHEMBL148953

SCHEMBL148953

C=CCn1cc(N)c(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
TK1 P04183 8/20 0.36
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CNR1 P21554 1/20 0.33
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
TK2 O00142 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9021896 0.79 TK1 (0.56) TK1TK2
SCHEMBL17791229 0.79 CYP1A2 (0.49) CYP3A4CYP1A2CYP2D6TK1KMT2A
SCHEMBL4564516 0.79 GRIA1 (0.49) CYP1A2KMT2AALDH1A1
SCHEMBL4273433 0.78 DPYD (0.31)
SCHEMBL12410891 0.77 TK1 (0.41) CYP3A4CYP1A2CYP2D6TK1MAPT
SCHEMBL2248519 0.75 KMT2A (0.52) CYP3A4CYP1A2CYP2C9KMT2AKDM4E
SCHEMBL1558433 0.73 TK2 (0.42) CYP3A4CYP1A2CYP2D6TK1KMT2A
SCHEMBL1558432 0.73 TK2 (0.42) CYP3A4CYP1A2CYP2D6TK1KMT2A
SCHEMBL17243367 0.73 KMT2A (0.36) CYP3A4CYP1A2CYP2D6TK1MAPT
SCHEMBL12410794 0.73 TK1 (0.42) CYP3A4CYP1A2CYP2D6TK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-10-16 US claimed
EP-4627084-A1 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS Camp4 Therapeutics Corporation (US) 2025-10-08 EP claimed
US-20250290072-A1 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-09-18 US claimed
US-20250250575-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-08-07 US claimed
US-20250243488-A1 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-07-31 US claimed
WO-2024119145-A9 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION (US) 2025-06-19 WO claimed
WO-2025111430-A1 CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL PRIME MEDICINE, INC. (US) 2025-05-30 WO claimed
EP-3887514-A2 THERAPEUTIC GENE EDITING FOR ELANE-ASSOCIATED DISEASE The Children's Medical Center Corporation (US) 2021-10-06 EP claimed
WO-2021067233-A1 BCL11A GUIDE AND BASE EDITOR DELIVERY THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2021-04-08 WO claimed
EP-3794130-A1 METHODS AND SYSTEMS FOR GUIDE RNA DESIGN AND USE Synthego Corporation (US) 2021-03-24 EP claimed
WO-2020112979-A9 THERAPEUTIC GENE EDITING FOR ELANE-ASSOCIATED DISEASE BAUER DANIEL E (US) 2020-07-23 WO claimed
WO-2020112979-A2 THERAPEUTIC GENE EDITING FOR ELANE-ASSOCIATED DISEASE BAUER DANIEL E (US) 2020-06-04 WO claimed
US-20200095582-A1 BCL11A GUIDE DELIVERY THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2020-03-26 US claimed
WO-2018218135-A1 BCL11A GUIDE DELIVERY THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2018-11-29 WO claimed
WO-2018118587-A1 MODIFIED POLYNUCLEOTIDES FOR ANTIVIRAL THERAPY AGENOVIR CORPORATION (US) 2018-06-28 WO claimed
WO-2014152909-A1 ALTERATION OF GENE EXPRESSION BY SYNTHETIC piRNAs AND BY ALTERATION OF piRNA FUNCTION IBIS BIOSCIENCES, INC. (US) 2014-09-25 WO claimed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS ABCB11, SLC10A1, SREBF1 CYP3A4 2776/4885CYP1A2 2781/4885CYP2D6 3096/4885
US-20250250575-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CPS1, CTPS1, CTPS2 CYP3A4 4372/4885CYP1A2 4226/4885CYP2D6 4299/4885
US-20250243488-A1 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS GRN, SNRPE, UPF1 CYP3A4 4875/4885CYP1A2 4840/4885CYP2D6 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.