Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24391371 | 0.86 | CA1 (0.43) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL6509909 | 0.82 | CA1 (0.43) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL1825874 | 0.78 | EGFR (0.49) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL791306 | 0.77 | CA2 (0.56) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL5409379 | 0.76 | CA2 (0.43) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL13201475 | 0.76 | ALDH1A1 (0.55) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL22952575 | 0.75 | CA2 (0.43) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL21046004 | 0.75 | CA2 (0.43) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL487585 | 0.75 | CA1 (0.59) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL14552695 | 0.75 | CA1 (0.43) | CA2CA1CA12CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022012-A1 | METHODS AND COMPOSITION FOR TREATING RESPIRATORY OBSTRUCTIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-04 | — | — | WO | disclosed |
| WO-2020198529-A1 | SUBSTITUTED AMINO-THIOL AND AMINO-DISULFIDE COMPOUNDS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OFCALIFORNIA (US) | 2020-10-01 | — | — | WO | disclosed |