SCHEMBL22490887

SCHEMBL22490887

COc1cc(C(=O)OCO[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2O)cc(Cl)c1OCc1cccc(OC(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
LGALS9 O00182 1/20 0.34
LGALS8 O00214 1/20 0.34
LGALS1 P09382 1/20 0.34
LGALS3 P17931 1/20 0.34
LGALS7; LGALS7B P47929 1/20 0.34
SLC5A2 P31639 2/20 0.34
KDM4E B2RXH2 1/20 0.33
ADCYAP1R1 P41586 1/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
ACP1 P24666 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22490884 0.86 LGALS8 (0.35) ALDH1A1LGALS9LGALS8LGALS1LGALS3
SCHEMBL23488588 0.86 LGALS3 (0.40) ALDH1A1LGALS9LGALS8LGALS1LGALS3
SCHEMBL23488537 0.79 CA2 (0.44) ALDH1A1LGALS9LGALS8LGALS1LGALS3
SCHEMBL23488633 0.79 LGALS3 (0.46) ALDH1A1LGALS9LGALS8LGALS1LGALS3
SCHEMBL23488703 0.77 LGALS8 (0.37) LGALS9LGALS8LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL22490890 0.76 MRGPRX4 (0.50) KDM4EPTPN2PTPN1ACP1
SCHEMBL23488734 0.76 LGALS3 (0.40) ALDH1A1LGALS9LGALS8LGALS1LGALS3
SCHEMBL23488445 0.73 LGALS3 (0.40) LGALS9LGALS8LGALS1LGALS3LGALS7; LGALS7B
SCHEMBL23488610 0.73 LGALS8 (0.47) ALDH1A1LGALS9LGALS8LGALS1LGALS3
SCHEMBL23488628 0.73 LGALS8 (0.49) ALDH1A1LGALS9LGALS8LGALS1LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-3717463-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 ALDH1A1 1627/4885LGALS9 106/4885LGALS8 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.