SCHEMBL22490889

SCHEMBL22490889

Brc1ccc(-c2ccccc2)[c]c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPK1 P28482 2/20 0.38
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10324889 0.76 BACE1 (0.36) ALDH1A1MAPK1
SCHEMBL10814810 0.69 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL22490891 0.69 ALDH1A1 (0.37) ALDH1A1MAPK1TDP1
SCHEMBL2159260 0.69 TP53 (0.33) ALDH1A1
SCHEMBL15455683 0.69 GABRA1 (0.33)
SCHEMBL10747898 0.69 LTA4H (0.41) ALDH1A1
SCHEMBL9855959 0.68 ALDH1A1 (0.39) ALDH1A1MAPK1CRHBPCRHR2TDP1
SCHEMBL379055 0.68 ALDH1A1 (0.47) ALDH1A1MAPK1TDP1
SCHEMBL14164639 0.67 KDM4E (0.32) ALDH1A1
SCHEMBL617580 0.67 ALDH1A1 (0.53) ALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3717495-A1 PHOSPHORESCENT PLATINUM (II) ANHC COMPLEXES Technische Universität Dresden (DE) 2020-10-07 EP disclosed