SCHEMBL22490909

SCHEMBL22490909

COc1c(C(=O)O[C@@H]2[C@@H](OC)[C@@H](O)[C@@H](CO)O[C@@H]2O)cc(Cl)c(OCc2ccccc2)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 6/20 0.42
LGALS3 P17931 8/20 0.37
LGALS9 O00182 5/20 0.37
LGALS1 P09382 5/20 0.37
LGALS7; LGALS7B P47929 5/20 0.37
LGALS4 P56470 2/20 0.36
SLC5A2 P31639 2/20 0.35
PDE4D Q08499 1/20 0.35
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488625 0.88 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488453 0.88 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL22490910 0.83 LGALS8 (0.37) LGALS8LGALS3SLC5A2PDE4DLMNA
SCHEMBL23488647 0.79 LGALS3 (0.44) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488619 0.79 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488287 0.79 LGALS3 (0.47) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488706 0.78 CA2 (0.47) LGALS8LGALS3LGALS1LGALS7; LGALS7B
SCHEMBL23488312 0.78 CA2 (0.47) LGALS8LGALS3LGALS1LGALS7; LGALS7B
SCHEMBL22490855 0.77 LGALS3 (0.50) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL22490919 0.77 LGALS3 (0.50) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed
EP-3717463-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN Sanofi (FR) 2020-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS8 61/4885LGALS3 156/4885LGALS9 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.