Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22773228 | 0.87 | MAPT (0.47) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL892836 | 0.81 | OPRM1 (0.53) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL30567991 | 0.81 | OPRM1 (0.53) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL4771971 | 0.81 | AVPR1A (0.50) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1703941 | 0.80 | OPRM1 (0.52) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL24377767 | 0.79 | KDM4E (0.47) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL4674153 | 0.79 | HSD11B1 (0.60) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL4882143 | 0.79 | DRD2 (0.56) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL21384720 | 0.78 | KDM4E (0.47) | MAPTKDM4ETHRBBRD4ALDH1A1 | |
| SCHEMBL8618496 | 0.77 | CYP1A2 (0.63) | MAPTKDM4ETHRBBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-A1 | NEW HETEROCYCLIC COMPOUNDS | H. Hoffnabb-La Roche Ag (CH) | 2020-10-07 | — | — | EP | disclosed |