SCHEMBL22492333

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27371112	0.86	LMNA (0.50)	SMN1; SMN2KDM4EMEN1KMT2AALDH1A1
	SCHEMBL27371109	0.83	ATR (0.56)	SMN1; SMN2KDM4EMEN1KMT2AALDH1A1
	SCHEMBL30647636	0.83	LMNA (0.50)	KDM4EMEN1KMT2AALDH1A1LMNA
	SCHEMBL26965973	0.83	LMNA (0.50)	KDM4EMEN1KMT2AALDH1A1LMNA
	SCHEMBL24728976	0.80	LMNA (0.52)	KDM4EMEN1KMT2ALMNAPSMD14
	SCHEMBL22492429	0.80	LMNA (0.52)	SMN1; SMN2TDP1KDM4EKMT2AALDH1A1
	SCHEMBL30647543	0.80	LMNA (0.52)	KDM4EMEN1KMT2ALMNAPSMD14
	SCHEMBL22492342	0.78	PLA2G2A (0.54)	KDM4ELMNAPSMD14
	SCHEMBL22492354	0.78	KDM4E (0.54)	KDM4EMEN1KMT2AALDH1A1LMNA
	SCHEMBL20074656	0.78	L3MBTL1 (0.62)	SMN1; SMN2KDM4EALDH1A1LMNAPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.