Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MDH1 | P40925 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491610 | 0.86 | MEN1 (0.69) | MEN1KMT2APOLBSMN1; SMN2TACR3 | |
| SCHEMBL19702689 | 0.85 | LIPE (0.50) | MEN1KMT2APOLBMDH1MDH2 | |
| SCHEMBL22493089 | 0.85 | LIPE (0.50) | MEN1KMT2APOLBMDH1MDH2 | |
| SCHEMBL22492925 | 0.83 | MEN1 (0.52) | MEN1KMT2APOLBSMN1; SMN2TACR3 | |
| SCHEMBL19702661 | 0.83 | MDH1 (0.48) | MEN1KMT2APOLBMDH1MDH2 | |
| SCHEMBL19702599 | 0.82 | MDH1 (0.47) | MEN1KMT2APOLBMDH1MDH2 | |
| SCHEMBL19702709 | 0.82 | MDH1 (0.52) | MDH1MDH2ENPP2MAPTALDH1A1 | |
| SCHEMBL19702293 | 0.81 | MDH1 (0.48) | MDH1MDH2ENPP2SMN1; SMN2MAPT | |
| SCHEMBL19703084 | 0.81 | MDH1 (0.48) | MDH1MDH2ENPP2SMN1; SMN2MAPT | |
| SCHEMBL19702954 | 0.81 | MDH1 (0.46) | MEN1KMT2APOLBMDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200306248-A1 | FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME | GDD THERAPEUTICS, LLC (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200306248-A1 | FORMULATIONS FOR SUBSTITUTED 3-PYRROLIDINES, COMPOSITIONS CONTAINING, AND USES OF, SAME | SLC7A1, ABCG2, SLC46A1 | MEN1 3103/4885KMT2A 4536/4885POLB 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.