Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493402 | 0.80 | P2RX7 (0.37) | GRM5 | |
| SCHEMBL22493349 | 0.77 | GRM5 (0.35) | ALDH1A1MTNR1AKDM4EHRH3HTR2A | |
| SCHEMBL22493463 | 0.76 | HTR2A (0.48) | MTNR1AHTR2AHTR2CSLC13A5 | |
| SCHEMBL22493867 | 0.76 | CD38 (0.38) | ALDH1A1TP53BP1MTNR1AKDM4ETAAR1 | |
| SCHEMBL22864232 | 0.76 | HDAC6 (0.46) | ALDH1A1KDM4ELMNAALOX15 | |
| SCHEMBL26853974 | 0.76 | MAPK1 (0.34) | ALDH1A1CYP1A2CYP2C19MTNR1AKDM4E | |
| SCHEMBL23641297 | 0.75 | GRM5 (0.44) | ALDH1A1KDM4EGRM5 | |
| SCHEMBL22493347 | 0.75 | KCNN4 (0.44) | ALDH1A1KDM4ETRPV1 | |
| SCHEMBL26854073 | 0.75 | SLC13A5 (0.49) | KDM4EHTR2AHTR2CSLC13A5LMNA | |
| SCHEMBL13712999 | 0.74 | TKT (0.38) | ALDH1A1CYP1A2KDM4ESLC13A5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225021-A1 | COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS (ALS) | CURASEN THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |