Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HTR5A | P47898 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864224 | 0.82 | SLC40A1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL22864223 | 0.81 | ALDH1A1 (0.42) | HDAC6MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22864227 | 0.80 | METAP2 (0.44) | MEN1KMT2ARAB9AGLO1SMN1; SMN2 | |
| SCHEMBL22864222 | 0.80 | ALDH1A1 (0.34) | MEN1KMT2AKDM4EMAPTCYP2D6 | |
| SCHEMBL22493402 | 0.79 | P2RX7 (0.37) | — | |
| SCHEMBL22864147 | 0.78 | PSMD14 (0.46) | KMT2ANPC1HTTKDM4EMAPT | |
| SCHEMBL22864229 | 0.77 | CCR1 (0.41) | MEN1KMT2ANPC1RAB9AALOX15 | |
| SCHEMBL1709266 | 0.76 | KDM4E (0.50) | HDAC6HTR5AMEN1KMT2ANPC1 | |
| SCHEMBL11497619 | 0.76 | HDAC6 (0.47) | HDAC6HTR5AMEN1KMT2ANPC1 | |
| SCHEMBL19272587 | 0.76 | HDAC6 (0.44) | HDAC6HTR5AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003161-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |