Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26854073 | 0.86 | SLC13A5 (0.49) | HTR2AHTR2CSLC13A5SLC6A2SLC6A4 | |
| SCHEMBL22493402 | 0.79 | P2RX7 (0.37) | GRIN1GRIN2B | |
| SCHEMBL23355293 | 0.79 | HTR2A (0.44) | HTR2AHTR2CSLC13A5KDM1AMAOA | |
| SCHEMBL12093550 | 0.76 | SLC13A5 (0.51) | HTR2AHTR2CSLC13A5KDM1AMAOA | |
| SCHEMBL22493349 | 0.76 | GRM5 (0.35) | HTR2AHTR2CMTNR1A | |
| SCHEMBL22493346 | 0.76 | ALDH1A1 (0.33) | HTR2AHTR2CSLC13A5MTNR1A | |
| SCHEMBL8220219 | 0.76 | SLC13A5 (0.48) | HTR2AHTR2CSLC13A5KDM1AMAOA | |
| SCHEMBL22493867 | 0.75 | CD38 (0.38) | GAAGRIN1GRIN2BMTNR1A | |
| SCHEMBL22864232 | 0.75 | HDAC6 (0.46) | GAA | |
| SCHEMBL26853974 | 0.75 | MAPK1 (0.34) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |