Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493465 | 0.84 | KCNA5 (0.40) | KCNN4KCNA5TRPV1KDM4E | |
| SCHEMBL22493402 | 0.78 | P2RX7 (0.37) | — | |
| SCHEMBL22493349 | 0.75 | GRM5 (0.35) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL22493346 | 0.75 | ALDH1A1 (0.33) | TRPV1ALDH1A1KDM4E | |
| SCHEMBL18778553 | 0.74 | GPR84 (0.44) | KCNN4KCNA5ALDH1A1PTGS1PTGS2 | |
| SCHEMBL22493867 | 0.74 | CD38 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL22864232 | 0.74 | HDAC6 (0.46) | ALDH1A1HIF1AKDM4EKMT2A | |
| SCHEMBL22493463 | 0.74 | HTR2A (0.48) | SLC22A12 | |
| SCHEMBL26853974 | 0.74 | MAPK1 (0.34) | KCNA5TRPV1ALDH1A1KDM4E | |
| SCHEMBL21973538 | 0.73 | PTGS1 (0.46) | KCNN4KCNA5TRPV1ALDH1A1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137506-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023225021-A1 | COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS (ALS) | CURASEN THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2020198466-A9 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020198466-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |