Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | ACE | P12821 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494092 | 1.00 | FAAH (0.61) | FAAHALDH1A1MAPTEPHX2ACE | |
| SCHEMBL26624454 | 0.94 | FAAH (0.64) | FAAHALDH1A1MAPTEPHX2ACE | |
| SCHEMBL26624443 | 0.94 | FAAH (0.64) | FAAHALDH1A1MAPTEPHX2ACE | |
| SCHEMBL22494111 | 0.93 | FAAH (0.68) | FAAHALDH1A1MAPTEPHX2ACE | |
| SCHEMBL22494113 | 0.93 | FAAH (0.68) | FAAHALDH1A1MAPTEPHX2ACE | |
| SCHEMBL31026991 | 0.91 | FAAH (0.73) | FAAHEPHX2CNR1CNR2 | |
| SCHEMBL15285026 | 0.90 | FAAH (0.76) | FAAHEPHX2CNR1CNR2 | |
| SCHEMBL18585828 | 0.85 | ALOX12 (0.63) | FAAHALDH1A1MAPTACEMME | |
| SCHEMBL18619563 | 0.85 | ALOX12 (0.63) | FAAHALDH1A1MAPTACEMME | |
| SCHEMBL18585826 | 0.85 | ALOX12 (0.63) | FAAHALDH1A1MAPTACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-21 | — | — | US | disclosed |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365177-B2 | Chemical uncouplers of respiration and methods of use thereof | PC, UQCRC1, SQOR | FAAH 1063/4885ALDH1A1 352/4885MAPT 4698/4885 |
| US-20200317613-A1 | CHEMICAL UNCOUPLERS OF RESPIRATION AND METHODS OF USE THEREOF | PC, UQCRC1, SQOR | FAAH 1063/4885ALDH1A1 352/4885MAPT 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.