SCHEMBL22496629

SCHEMBL22496629

N#Cc1c(F)c(Br)cc(Br)c1F

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.41
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
ALB P02768 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30435544 0.78 TRPV4 (0.46) TRPV4MEN1TTRALBKMT2A
SCHEMBL17188083 0.75 KDM4E (0.33) TRPV4MEN1KMT2AKDM4EHPGD
SCHEMBL1727262 0.74 TRPV4 (0.41) TRPV4MEN1TTRALBKMT2A
SCHEMBL15406588 0.74 TTR (0.58) TRPV4MEN1TTRALBKMT2A
SCHEMBL29017429 0.73 TRPV4 (0.42) TRPV4HTT
SCHEMBL29450561 0.73 TRPV4 (0.37) TRPV4KDM4EHPGD
SCHEMBL2729265 0.73 TRPV4 (0.37) TRPV4KDM4EHPGD
SCHEMBL9625848 0.73 TRPV4 (0.41) TRPV4MEN1KMT2AHPGD
SCHEMBL57543 0.73 TRPV4 (0.41) TRPV4MEN1KMT2AHPGD
SCHEMBL3474652 0.72 TRPV4 (0.33) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11453682-B2 Condensed-cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-09-27 US disclosed
US-20200317694-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200317694-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, CCNA1 TRPV4 2065/4885MEN1 141/4885TTR 3273/4885
US-11453682-B2 Condensed-cyclic compound and organic light-emitting device including the same CRY1, CCNT1, CCNA1 TRPV4 2065/4885MEN1 141/4885TTR 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.