Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852140 | 0.75 | AHR (0.32) | — | |
| SCHEMBL407685 | 0.68 | ALDH1A1 (0.42) | MAPTALDH1A1NPSR1KMT2AHTR2A | |
| Chloroneb SCHEMBL22739 | 0.67 | GAA (0.64) | GAANPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL22509234 | 0.67 | PGK1 (0.48) | GAANPC1PGK1 | |
| SCHEMBL27884136 | 0.67 | CYP19A1 (0.42) | MAPTALDH1A1POLB | |
| SCHEMBL26654511 | 0.66 | S100B (0.62) | GAANPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL16727210 | 0.66 | LMNA (0.40) | GAANPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL16609990 | 0.65 | GAA (0.68) | GAANPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL30487990 | 0.63 | GAA (0.65) | GAANPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL3757554 | 0.63 | NPC1 (0.65) | GAANPC1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020200158-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | 深圳福沃药业有限公司 | 2020-10-08 | — | — | WO | claimed |
| WO-2020200158-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | 深圳福沃药业有限公司 | 2020-10-08 | — | — | WO | disclosed |