Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451486 | 0.86 | LMNA (0.41) | SMN1; SMN2TDP1TSHRLMNAALDH1A1 | |
| SCHEMBL13172586 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2TDP1TSHRLMNAALDH1A1 | |
| SCHEMBL2939462 | 0.76 | HTR1A (0.35) | — | |
| SCHEMBL2946834 | 0.76 | ERN1 (0.35) | — | |
| SCHEMBL2949836 | 0.76 | ERN1 (0.35) | — | |
| SCHEMBL22070616 | 0.73 | HCRTR2 (0.33) | — | |
| SCHEMBL22070983 | 0.73 | HCRTR2 (0.33) | — | |
| SCHEMBL22520089 | 0.73 | MAPT (0.41) | SMN1; SMN2TDP1LMNAALDH1A1MAPT | |
| SCHEMBL28841519 | 0.72 | HCRTR1 (0.40) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22071102 | 0.72 | DRD2 (0.37) | SMN1; SMN2TDP1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020202091-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020202091-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-10-08 | — | — | WO | disclosed |