SCHEMBL22500545

SCHEMBL22500545

Cc1ccc(S(=O)(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NC(C)C)cc1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 2/20 0.70
MMP2 P08253 11/20 0.69
MMP9 P14780 10/20 0.69
AIMP2 Q13155 2/20 0.64
KCNA5 P22460 4/20 0.61
MMP1 P03956 1/20 0.58
MMP14 P50281 1/20 0.58
KCNH2 Q12809 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22501220 1.00 NR3C1 (0.70) NR3C1MMP2MMP9AIMP2KCNA5
SCHEMBL22501080 0.91 MMP9 (0.77) NR3C1MMP2MMP9AIMP2KCNA5
SCHEMBL22501078 0.91 MMP9 (0.77) NR3C1MMP2MMP9AIMP2KCNA5
SCHEMBL22500228 0.91 MMP9 (0.68) NR3C1MMP2MMP9KCNA5MMP1
SCHEMBL22500613 0.91 MMP9 (0.68) NR3C1MMP2MMP9KCNA5MMP1
SCHEMBL22501128 0.91 MMP9 (0.77) NR3C1MMP2MMP9AIMP2KCNA5
SCHEMBL22501031 0.88 MMP2 (0.65) NR3C1MMP2MMP9AIMP2KCNA5
SCHEMBL22501033 0.88 MMP2 (0.65) NR3C1MMP2MMP9AIMP2KCNA5
SCHEMBL22500772 0.88 AIMP2 (0.75) NR3C1MMP2MMP9AIMP2
SCHEMBL22500769 0.88 AIMP2 (0.75) NR3C1MMP2MMP9AIMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204497-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2022-06-30 US claimed
EP-3939968-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME Medicinal Bioconvergence Research Center (KR) 2022-01-19 EP claimed
WO-2020204548-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME 재단법인 의약바이오컨버젼스연구단 2020-10-08 WO claimed
US-20220204497-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2022-06-30 US disclosed
EP-3939968-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME Medicinal Bioconvergence Research Center (KR) 2022-01-19 EP disclosed
WO-2020204548-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME 재단법인 의약바이오컨버젼스연구단 2020-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204497-A1 NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME TPX2, AIMP2, CDYL2 NR3C1 4365/4885MMP2 3511/4885MMP9 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.