Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252168 | 0.90 | L3MBTL1 (0.35) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL9821944 | 0.83 | ALDH1A1 (0.44) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL2256411 | 0.80 | ALDH1A1 (0.33) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL12566478 | 0.77 | ALDH1A1 (0.48) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL2701042 | 0.77 | CYP1A2 (0.41) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL2251091 | 0.73 | ALDH1A1 (0.39) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL27642965 | 0.73 | ALDH1A1 (0.35) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL2253620 | 0.72 | KDM4E (0.47) | CYP1A2ALDH1A1HSD17B10HPGDCYP2A6 | |
| SCHEMBL5749295 | 0.72 | HTR2A (0.44) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL2252060 | 0.72 | KDM4E (0.36) | CYP1A2ALDH1A1HSD17B10HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916244-B1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-12-04 | — | — | EP | disclosed |
| EP-1882694-B1 | OLIGOMERS AND POLYMERS OF THIOPHENE COMPOUNDS HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL IND LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-8008425-B2 | Thiophene compound having sulfonyl group and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| US-20090127491-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1916244-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090127491-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | TST, ABCG2, CBR3 | CYP1A2 249/4885ALDH1A1 1104/4885HSD17B10 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.