Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459660 | 0.94 | PAM (0.37) | PAMDGKACES2CES1AKR1B1 | |
| SCHEMBL28437701 | 0.86 | ALDH1A1 (0.44) | CES2CES1LMNAPPARGPPARA | |
| SCHEMBL28022796 | 0.86 | PAM (0.47) | PAMDGKALMNAPPARGPPARD | |
| SCHEMBL28022715 | 0.86 | PAM (0.47) | PAMDGKALMNAPPARGPPARD | |
| SCHEMBL28246112 | 0.86 | PAM (0.47) | PAMDGKALMNAPPARGPPARD | |
| SCHEMBL8997387 | 0.86 | PAM (0.51) | PAMDGKALMNAPPARGPPARD | |
| SCHEMBL5497362 | 0.84 | LMNA (0.51) | PAMDGKALMNAALDH1A1MEN1 | |
| SCHEMBL28520119 | 0.82 | MAPT (0.49) | PAMDGKALMNAMEN1KMT2A | |
| SCHEMBL5365642 | 0.80 | MAPT (0.51) | PAMDGKALMNAMEN1KMT2A | |
| SCHEMBL27734730 | 0.80 | MAPT (0.51) | PAMDGKALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10471173-B2 | Conformable composition for skin applications | ALCARE CO., LTD. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20170232136-A1 | CONFORMABLE COMPOSITION FOR SKIN APPLICATIONS | ALCARE CO., LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3187198-A1 | MOLDABLE COMPOSITION FOR SKIN APPLICATIONS | Alcare Co., Ltd. (JP) | 2017-07-05 | — | — | EP | disclosed |
| EP-2517712-B1 | Composition for reducing skin dullness | OTSUKA PHARMA CO LTD (JP) | 2017-05-10 | — | — | EP | disclosed |
| EP-1512405-B1 | COMPOSITION COMPRISING ADENOSINE MONOPHOSPHATE FOR TREATING MELASMA | OTSUKA PHARMA CO LTD (JP) | 2013-08-14 | — | — | EP | disclosed |
| EP-2517712-A1 | Composition for improving melasma and composition for reducing skin dullness | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-7994153-B2 | Chloasma amelioration composition and dullness amelioration composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| CN-100341486-C | Oil-in-water type emulsion composition and method for producing the same | OTSUKA PHARMA CO LTD (JP) | 2007-10-10 | — | — | CN | disclosed |
| US-20050220827-A1 | Chloasma amelioration composition and dullness amelioration composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| EP-1512405-A1 | CHLOASMA AMELIORATION COMPOSITION AND DULLNESS AMELIORATION COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-09 | — | — | EP | disclosed |
| CN-1476318-A | Oil-in-water type emulsion composition and method for producing the same | ��V��ҩ��ʽ���� | 2004-02-18 | — | — | CN | disclosed |
| EP-0333373-B1 | Method for synthesizing acyloxycarboxylic acids | CLOROX CO (US) | 1995-01-04 | — | — | EP | disclosed |