Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365642 | 0.98 | MAPT (0.51) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL27734730 | 0.98 | MAPT (0.51) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL27603184 | 0.97 | MAPT (0.50) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9579019 | 0.87 | LMNA (0.50) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL4153858 | 0.85 | MAPT (0.46) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL27496716 | 0.82 | MAPT (0.53) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL2250835 | 0.82 | PAM (0.46) | LMNAMEN1KMT2APAMDGKA | |
| SCHEMBL27952502 | 0.81 | MAPT (0.56) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL8997387 | 0.79 | PAM (0.51) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28246112 | 0.79 | PAM (0.47) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107115326-B | Skin pharmaceutical composition of 1-methyl-N- (2, 6-xylyl) -2-piperidine formamide and using method thereof | 雷尔玛达治疗股份有限公司 | 2021-01-22 | — | — | CN | disclosed |