Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 6/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | NMBR | P28336 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22508709 | 0.81 | CTSS (0.49) | CTSSCTSKCTSL | |
| SCHEMBL7351535 | 0.75 | ACHE (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20542752 | 0.71 | SIRT1 (0.70) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| SCHEMBL20542735 | 0.71 | SIRT1 (0.70) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| SCHEMBL20542632 | 0.71 | SIRT1 (0.70) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| SCHEMBL20542736 | 0.71 | SIRT1 (0.70) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| Hydrochloric Acid SCHEMBL20542921 | 0.70 | SIRT1 (0.69) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| Hydrochloric Acid SCHEMBL20542923 | 0.70 | SIRT1 (0.69) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| Hydrochloric Acid SCHEMBL20542761 | 0.70 | SIRT1 (0.69) | SIRT1SIRT6SIRT2SIRT3TLR2 | |
| Hydrochloric Acid SCHEMBL20542763 | 0.70 | SIRT1 (0.69) | SIRT1SIRT6SIRT2SIRT3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030545-B1 | AMINO ACID DERIVATIVES | MEDIMMUNE LTD (GB) | 2020-10-07 | — | — | EP | disclosed |