Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.49 |
| ▸ | CTSK | P43235 | 13/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029765 | 0.89 | CTSS (0.53) | CTSSCTSKCAPN1CA2CTSL | |
| SCHEMBL14030568 | 0.88 | CTSS (0.52) | CTSSCTSKCAPN1CA2CTSL | |
| SCHEMBL14029867 | 0.83 | CA1 (0.53) | CTSSCTSKCAPN1CA2 | |
| SCHEMBL14029767 | 0.82 | CTSK (0.53) | CTSSCTSKCAPN1CA2CTSL | |
| SCHEMBL1023991 | 0.81 | CTSK (0.55) | CTSSCTSKCAPN1CA2CTSL | |
| SCHEMBL14029771 | 0.81 | CTSS (0.51) | CTSSCTSKCAPN1CA2CTSL | |
| SCHEMBL22508702 | 0.81 | SIRT1 (0.40) | CTSSCTSKCTSL | |
| SCHEMBL14030531 | 0.80 | CTSS (0.54) | CTSSCTSKCAPN1CA2 | |
| SCHEMBL16627725 | 0.79 | CTSK (0.46) | CTSSCTSKCAPN1CA2CTSL | |
| SCHEMBL7762812 | 0.79 | CTSK (0.50) | CTSSCTSKCA2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030545-B1 | AMINO ACID DERIVATIVES | MEDIMMUNE LTD (GB) | 2020-10-07 | — | — | EP | disclosed |