Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18114419 | 0.91 | SRC (0.46) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL19463373 | 0.80 | CDK8 (0.38) | HDAC4MEF2DTRIM24TRIM33BRD4 | |
| SCHEMBL28376632 | 0.79 | SRC (0.42) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL29664363 | 0.79 | SRC (0.42) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL26345121 | 0.79 | SRC (0.42) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL28371609 | 0.79 | SRC (0.42) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL29664399 | 0.79 | SRC (0.42) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL29588562 | 0.79 | SRC (0.42) | HDAC4MEF2DSRCMAOAMAOB | |
| SCHEMBL19463138 | 0.79 | CDK8 (0.35) | HDAC4MEF2DTRIM24TRIM33CA12 | |
| SCHEMBL15748348 | 0.77 | ENPP2 (0.52) | HDAC4MEF2DDRD1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200325154-A1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES WITH OXETANE-3-YLOXY SUBSTITUTION | ACTELION PHARMACEUTICALS LTD (CH) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325154-A1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES WITH OXETANE-3-YLOXY SUBSTITUTION | MT-CO3, UQCRC1, MT-ND3 | HDAC4 2120/4885MEF2D 365/4885DRD1 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.