Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17687826 | 0.82 | SLC6A2 (0.41) | SLC6A2SLC6A4KCNH2FFAR4CDK8 | |
| SCHEMBL17687955 | 0.81 | FFAR4 (0.45) | SLC6A2SLC6A4KCNH2FFAR4BRD4 | |
| SCHEMBL19471860 | 0.80 | FFAR4 (0.44) | SLC6A2SLC6A4KCNH2FFAR4 | |
| SCHEMBL17687988 | 0.80 | FFAR4 (0.44) | SLC6A2SLC6A4KCNH2FFAR4 | |
| SCHEMBL19471785 | 0.80 | FFAR4 (0.44) | SLC6A2SLC6A4KCNH2FFAR4 | |
| SCHEMBL17687912 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4KCNH2FFAR4CDK8 | |
| SCHEMBL17687802 | 0.78 | FFAR4 (0.47) | SLC6A2SLC6A4KCNH2FFAR4PIM1 | |
| SCHEMBL19463373 | 0.78 | CDK8 (0.38) | CDK8BRD4KMOMTORTRIM24 | |
| SCHEMBL22528205 | 0.77 | HDAC4 (0.42) | SLC6A2SLC6A4FFAR4CDK8BRD4 | |
| SCHEMBL19463138 | 0.77 | CDK8 (0.35) | CDK8BRD4KMOMTORTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200325154-A1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES WITH OXETANE-3-YLOXY SUBSTITUTION | ACTELION PHARMACEUTICALS LTD (CH) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325154-A1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES WITH OXETANE-3-YLOXY SUBSTITUTION | MT-CO3, UQCRC1, MT-ND3 | SLC6A2 3906/4885SLC6A4 4475/4885KCNH2 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.