SCHEMBL225451

SCHEMBL225451

C=CNC(=O)c1ccccc1C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.45
ALDH1A1 P00352 5/20 0.45
HPGD P15428 4/20 0.45
MAPT P10636 3/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 1/20 0.45
METAP2 P50579 1/20 0.42
BCAT2 O15382 1/20 0.41
PARP1 P09874 1/20 0.40
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
LMNA P02545 1/20 0.39
SIRT2 Q8IXJ6 2/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
NFKB1 P19838 1/20 0.38
CASP1 P29466 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL11829658 0.93 KDM4E (0.43) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL5884981 0.82 ALDH1A1 (0.56) KDM4EALDH1A1HPGDMAPTPOLB
SCHEMBL21457763 0.82 IKBKB (0.46) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL21457542 0.81 PARP1 (0.44) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL7313032 0.81 ALDH1A1 (0.49) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL7315153 0.78 KDM4E (0.59) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL17766647 0.77 ALDH1A1 (0.54) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL6597631 0.77 HPGD (0.55) KDM4EALDH1A1HPGDNPC1TP53
SCHEMBL31097065 0.77 POLB (0.62) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL27986473 0.77 GAA (0.58) ALDH1A1HPGDMAPTLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
US-9151968-B2 Integrated optical waveguide interferometric sensor OPTISENSE B.V. (NL) 2015-10-06 US claimed
EP-2551102-B1 Self-stick foam adhesive 3M INNOVATIVE PROPERTIES CO (US) 2014-12-03 EP claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
WO-2010089209-A1 INTEGRATED OPTICAL WAVEGUIDE INTERFEROMETRIC SENSOR OPTISENSE B.V. (NL) 2010-08-12 WO claimed
EP-2214049-A1 Integrated optical waveguide interferometric sensor Optisense B.V. (NL) 2010-08-04 EP claimed
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same ROCHAL TECHNOLOGIES LLC (US) 2023-12-12 US disclosed
CN-109694655-B Adhesive sheet and display 琳得科株式会社 2023-05-02 CN disclosed
CN-107239008-B Image forming apparatus and process cartridge 富士胶片商业创新有限公司 2022-03-11 CN disclosed
CN-110603124-B Transparent wood and preparation method thereof 切卢特克股份公司 2022-03-04 CN disclosed
CN-107515518-B Endless belt, image forming apparatus, and endless belt unit 富士胶片商业创新有限公司 2021-11-09 CN disclosed
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP disclosed
US-4695288-A Subbing layer for dye-donor element used in thermal dye transfer EASTMAN KODAK COMPANY (US) 1987-09-22 US disclosed
US-4582724-A Chemical Bonding Agent for the suppression of \"rusty bolt\" Intermodulation Interference THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1986-04-15 US disclosed
EP-0009795-B1 PHOTOGRAPHIC ELEMENT CONTAINING A TEMPORARY BARRIER LAYER BETWEEN REACTANTS AND POLYMERIC COMPOSITIONS USEFUL THEREIN EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-06-09 EP disclosed
US-4317892-A COPOLYMER OF A VINYL ESTER AND AN UNSATURATED ACID OR ANHYDRIDE MODIFIED BY AN ALKANOL; COLOR FILMS EASTMAN KODAK COMPANY (US) 1982-03-02 US disclosed
US-4229516-A Photographic material with temporary barrier layer comprising a mixture of vinylidene chloride terpolymer and polymeric carboxy-ester-lactone and photographic transfer process therefor EASTMAN KODAK COMPANY (US) 1980-10-21 US disclosed
EP-0009795-A2 Photographic element containing a temporary barrier layer between reactants and polymeric compositions useful therein EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839626-B2 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same CUTA, MMP8, MMP1 KDM4E 4848/4885ALDH1A1 4110/4885HPGD 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.