Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22545910 | 0.82 | HDAC3 (0.50) | HDAC1SIRT5CXCR3FOLH1 | |
| SCHEMBL22545908 | 0.75 | FOLH1 (0.38) | HDAC1SIRT5CXCR3NPY1RFOLH1 | |
| SCHEMBL22545937 | 0.73 | CHRM2 (0.48) | HDAC1FOLH1 | |
| SCHEMBL18725740 | 0.69 | CXCR3 (0.49) | CXCR3 | |
| SCHEMBL18725733 | 0.69 | CXCR3 (0.49) | CXCR3 | |
| SCHEMBL4727576 | 0.64 | KDM4E (0.78) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL18742006 | 0.63 | CPB2 (0.60) | CXCR3 | |
| SCHEMBL18725757 | 0.63 | CPB2 (0.60) | CXCR3 | |
| SCHEMBL18725756 | 0.63 | CPB2 (0.60) | CXCR3 | |
| SCHEMBL11545905 | 0.62 | NAAA (0.57) | HDAC1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210625-A1 | METHODS FOR MODULATING MACROPHAGE ACTIVITY | Riptide Bioscience, Inc. (US) | 2020-10-15 | — | — | WO | disclosed |