Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689717 | 0.88 | SIGMAR1 (0.68) | SIGMAR1OPRK1MEN1KMT2AHTT | |
| SCHEMBL20689711 | 0.88 | SIGMAR1 (0.68) | SIGMAR1OPRK1MEN1KMT2AHTT | |
| SCHEMBL20689709 | 0.88 | SIGMAR1 (0.68) | SIGMAR1OPRK1MEN1KMT2AHTT | |
| SCHEMBL19498803 | 0.84 | OPRK1 (0.81) | SIGMAR1OPRK1MEN1KMT2AADRB2 | |
| SCHEMBL28873445 | 0.81 | SIGMAR1 (0.68) | SIGMAR1OPRK1MEN1KMT2AHTT | |
| SCHEMBL19498805 | 0.77 | SIGMAR1 (0.74) | SIGMAR1OPRK1 | |
| SCHEMBL18435350 | 0.77 | SIGMAR1 (0.72) | SIGMAR1OPRK1SMN1; SMN2 | |
| SCHEMBL9360922 | 0.77 | SIGMAR1 (1.00) | SIGMAR1OPRK1ADRB2ADRB1HTR1A | |
| SCHEMBL19498788 | 0.77 | SIGMAR1 (1.00) | SIGMAR1OPRK1ADRB2ADRB1HTR1A | |
| SCHEMBL31734116 | 0.75 | OPRK1 (1.00) | SIGMAR1OPRK1MEN1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200325124-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325124-A1 | THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION | ABCB11, SLC47A1, SLC47A2 | SIGMAR1 1771/4885OPRK1 1007/4885MEN1 4183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.