Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22541290 | 0.88 | BRD4 (0.41) | BRD4HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL24334860 | 0.86 | BRD4 (0.40) | BRD4HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL22541280 | 0.85 | HSP90AA1 (0.38) | CCR3BRD4HSP90AA1HSP90AB1 | |
| SCHEMBL22548269 | 0.85 | CCR3 (0.39) | CCR3HSP90AA1HSP90AB1 | |
| SCHEMBL22541229 | 0.81 | BRD4 (0.47) | BRD4KCNH2HSP90AA1HSP90AB1 | |
| SCHEMBL22548219 | 0.81 | CCR2 (0.40) | BRD4HSP90AA1HSP90AB1 | |
| SCHEMBL22548154 | 0.81 | HSP90AA1 (0.39) | CCR3HSP90AA1HSP90AB1 | |
| SCHEMBL22541300 | 0.78 | HSP90AA1 (0.40) | BRD4HSP90AA1HSP90AB1KDM4EALDH1A1 | |
| SCHEMBL24477130 | 0.77 | BRD4 (0.44) | CCR3BRD4KCNH2HSP90AA1HSP90AB1 | |
| SCHEMBL22541216 | 0.77 | BRD4 (0.41) | CCR3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020207396-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2020-10-15 | — | — | WO | disclosed |