Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630757 | 0.88 | POLH (0.58) | POLHALOX5TOP2AACE2CNR1 | |
| SCHEMBL20630798 | 0.80 | POLH (0.70) | POLHALOX5TOP2ACSNK2A2CSNK2B | |
| SCHEMBL20630738 | 0.80 | POLH (0.70) | POLHALOX5TOP2ACSNK2A2CSNK2B | |
| SCHEMBL20631291 | 0.80 | POLH (0.53) | POLHALOX5TOP2AACE2CSNK2A2 | |
| SCHEMBL20630985 | 0.78 | POLH (0.64) | POLHALOX5TOP2ACSNK2A2CSNK2B | |
| SCHEMBL20631347 | 0.77 | POLH (0.63) | POLHALOX5TOP2ACSNK2A2CSNK2B | |
| SCHEMBL20631336 | 0.75 | POLH (0.64) | POLHALOX5TOP2ACSNK2A2CSNK2B | |
| SCHEMBL20631318 | 0.75 | POLH (0.67) | POLHALOX5TOP2ACSNK2A2CSNK2B | |
| SCHEMBL22548702 | 0.72 | POLH (0.68) | POLHALOX5TOP2AACE2EPHX2 | |
| SCHEMBL20630211 | 0.72 | POLH (0.67) | POLHALOX5TOP2ACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200323814-A1 | MEDICAL COMPOUND | VERA SALUS RICERCA S.R.L. (IT) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323814-A1 | MEDICAL COMPOUND | MTNR1B, CBR1, MTNR1A | POLH 3942/4885ALOX5 730/4885TOP2A 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.