SCHEMBL22551273

SCHEMBL22551273

C#CCNC(=O)CCCC#Cc1cnc(S(C)(=O)=O)nc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.32
▸ CYP3A4 P08684 2/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ CNR2 P34972 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CA12 O43570 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ CA14 Q9ULX7 1/20 0.31
▸ THRB P10828 1/20 0.30
▸ ITGB1 P05556 1/20 0.30
▸ ITGA4 P13612 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29263596 0.96 ALDH1A1 (0.35) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL22618750 0.88 FAAH (0.36) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL30674488 0.87 ALDH1A1 (0.32) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL22561348 0.87 ALDH1A1 (0.32) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL21137867 0.85 CYP1A2 (0.34) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL25045553 0.81 FFAR1 (0.32) ALDH1A1MAPT
SCHEMBL22618814 0.81 FFAR1 (0.32) ALDH1A1MAPTITGB1ITGA4
SCHEMBL22551277 0.81 FFAR1 (0.40) ALDH1A1MAPTITGB1ITGA4
SCHEMBL22618760 0.80 ITGB1 (0.41) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9
SCHEMBL30107915 0.80 ACACB (0.34) CYP1A2CYP3A4ALDH1A1MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086740-A1 USE AND METHOD OF BISPECIFIC ANTIBODY-DRUG CONJUGATES FOR TREATING TUMOR DISEASES SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2026-04-30 — — WO disclosed
WO-2026086737-A1 USES AND METHODS OF BISPECIFIC ANTIBODY-DRUG CONJUGATES FOR TREATING TUMOR DISEASES SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2026-04-30 — — WO disclosed
EP-3725798-B1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) 2026-03-04 — — EP disclosed
US-20260027224-A1 ANTIBODY-DRUG CONJUGATES TARGETING CDH3 AND PREPARATION METHODS AND USES THEREOF SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) 2026-01-29 — — US disclosed
EP-4673475-A1 ANTIBODY-DRUG CONJUGATES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF MULTITUDE THERAPEUTICS INC. (CN) 2026-01-07 — — EP disclosed
EP-4667495-A2 BIOACTIVE MOLECULE CONJUGATE, PREPARATION METHOD AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-12-24 — — EP disclosed
US-20250281631-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-09-11 — — US disclosed
EP-4603487-A1 HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-08-20 — — EP disclosed
EP-4603109-A1 ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-08-20 — — EP disclosed
EP-4601701-A1 ANTIBODY-DRUG CONJUGATE BINDING TO HUMAN PTK7 AND METHOD FOR PREPARATION AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-08-20 — — EP disclosed
CN-113683622-A Bioactive substance conjugate and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2021-11-23 — — CN disclosed
CN-113651831-A Bioactive substance conjugate and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2021-11-16 — — CN disclosed
CN-113603703-A Bioactive substance conjugate and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2021-11-05 — — CN disclosed
CN-111295389-B Bioactive substance conjugate and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2021-10-22 — — CN disclosed
US-20210101906-A2 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2021-04-08 — — US disclosed
US-20210101906-A2 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2021-04-08 — — US disclosed
US-20200347075-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2020-11-05 — — US disclosed
EP-3725798-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-10-21 — — EP disclosed
EP-3725798-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-10-21 — — EP disclosed
CN-111295389-A Bioactive substance conjugate and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2020-06-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027224-A1 ANTIBODY-DRUG CONJUGATES TARGETING CDH3 AND PREPARATION METHODS AND USES THEREOF H1-3, H1-4, H1-2 CYP1A2 2744/4885CYP3A4 2530/4885ALDH1A1 478/4885
US-20200347075-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA CYP1A2 3650/4885CYP3A4 3557/4885ALDH1A1 1175/4885
US-20210101906-A2 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA CYP1A2 3650/4885CYP3A4 3557/4885ALDH1A1 1175/4885
US-20250281631-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF TOP1, TOP2A, TOP2B CYP1A2 1890/4885CYP3A4 1205/4885ALDH1A1 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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