Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363093 | 0.88 | MMP2 (0.43) | MMP2NPSR1ITGB1ITGA4 | |
| SCHEMBL23193046 | 0.87 | MAPT (0.41) | ACACBSMN1; SMN2HPGDALDH1A1CYP3A4 | |
| SCHEMBL21137867 | 0.84 | CYP1A2 (0.34) | MMP2NPSR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL26528447 | 0.83 | MMP2 (0.36) | MMP2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24642861 | 0.82 | SMN1; SMN2 (0.36) | ACACBMMP2SMN1; SMN2GAAHPGD | |
| SCHEMBL22618750 | 0.82 | FAAH (0.36) | ACACBMMP2HPGDNPSR1ALDH1A1 | |
| SCHEMBL25046745 | 0.82 | MMP2 (0.32) | MMP2NPSR1ALDH1A1MAPT | |
| SCHEMBL22561348 | 0.81 | ALDH1A1 (0.32) | ALDH1A1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL30674488 | 0.81 | ALDH1A1 (0.32) | NPSR1ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL22551273 | 0.80 | CYP1A2 (0.32) | ALDH1A1CYP1A2CYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253035-A1 | ANTIBODY DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |