SCHEMBL22551376

SCHEMBL22551376

CC(C)=CCCC1(C)CC=NO1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579444 0.74 KMT2A (0.36) ALOX5PTGS1
Methyl Alcohol SCHEMBL28366343 0.72 KMT2A (0.34) ALOX5PTGS1
SCHEMBL22551377 0.70
Formaldehyde SCHEMBL28653660 0.69 TSHR (0.33) ALOX5PTGS1
Alcohol SCHEMBL28586780 0.69 ALOX15 (0.34) ALOX5PTGS1
SCHEMBL22551346 0.69
SCHEMBL17106180 0.66 KMT2A (0.32) ALOX5PTGS1
SCHEMBL24967630 0.66 KMT2A (0.57)
SCHEMBL22551344 0.66 AKT1 (0.38)
SCHEMBL6432189 0.66 ALOX5 (0.35) ALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113891882-B Process for producing dihydroisoxazole 组合化学工业株式会社 2024-11-26 CN disclosed
CN-112004805-B Process for producing 5, 5-disubstituted-4, 5-dihydroisoxazoles 组合化学工业株式会社 2024-06-14 CN disclosed
CN-117396464-A Process for producing aldehyde compound and dihydroisoxazole compound 组合化学工业株式会社 2024-01-12 CN disclosed
US-11753384-B2 Production method for 5,5-di-substituted-4,5-dihydroisoxazole KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2023-09-12 US disclosed
EP-3789382-B1 PRODUCTION METHOD FOR 5,5-DI-SUBSTITUTED-4,5-DIHYDROISOXAZOLE KUMIAI CHEMICAL INDUSTRY CO (JP) 2023-07-05 EP disclosed
WO-2023054702-A1 ALDEHYDE COMPOUND PRODUCTION METHOD AND DIHYDROISOXAZOLE COMPOUND PRODUCTION METHOD クミアイ化学工業株式会社 2023-04-06 WO disclosed
EP-3733652-B1 METHOD FOR PRODUCING THIOCARBOXAMIDINE SALT COMPOUND KUMIAI CHEMICAL INDUSTRY CO (JP) 2022-10-12 EP disclosed
CN-111491926-B Novel method for producing 5, 5-disubstituted-4, 5-dihydroisoxazole 组合化学工业株式会社 2022-07-15 CN disclosed
EP-3725782-B1 NOVEL METHOD FOR PRODUCING 5,5-DISUBSTITUTED-4,5-DIHYDROISOXAZOLE KUMIAI CHEMICAL INDUSTRY CO (JP) 2022-06-22 EP disclosed
CN-113891882-A Method for producing dihydroisoxazole 组合化学工业株式会社 2022-01-04 CN disclosed
EP-3789382-A1 PRODUCTION METHOD FOR 5,5-DI-SUBSTITUTED-4,5-DIHYDROISOXAZOLE Kumiai Chemical Industry Co., Ltd. (JP) 2021-03-10 EP disclosed
US-20210047280-A1 NOVEL METHOD FOR PRODUCING 5, 5-DISUBSTITUTED-4, 5-DIHYDROISOXAZOLE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2021-02-18 US disclosed
WO-2020251006-A1 METHOD FOR PRODUCING DIHYDROISOXAZOLE クミアイ化学工業株式会社 2020-12-17 WO disclosed
CN-112004805-A Process for producing 5, 5-disubstituted-4, 5-dihydroisoxazoles 组合化学工业株式会社 2020-11-27 CN disclosed
US-20200369631-A1 METHOD FOR PRODUCING THIOCARBOXAMIDINE SALT COMPOUND KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2020-11-26 US disclosed
US-10844024-B1 Method for producing thiocarboxamidine salt compound KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2020-11-24 US disclosed
EP-3733652-A1 METHOD FOR PRODUCING THIOCARBOXAMIDINE SALT COMPOUND Kumiai Chemical Industry Co., Ltd. (JP) 2020-11-04 EP disclosed
EP-3725782-A1 NOVEL METHOD FOR PRODUCING 5,5-DISUBSTITUTED-4,5-DIHYDROISOXAZOLE Kumiai Chemical Industry Co., Ltd. (JP) 2020-10-21 EP disclosed
CN-111542514-A Process for producing mercaptoformamidinate compound 组合化学工业株式会社 2020-08-14 CN disclosed
CN-111491926-A Novel method for producing 5, 5-disubstituted-4, 5-dihydroisoxazoles 组合化学工业株式会社 2020-08-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047280-A1 NOVEL METHOD FOR PRODUCING 5, 5-DISUBSTITUTED-4, 5-DIHYDROISOXAZOLE CYP3A5, CYP4X1, SQLE ALOX5 117/4885PTGS1 1033/4885
US-10844024-B1 Method for producing thiocarboxamidine salt compound TST, CBR3, NISCH ALOX5 673/4885PTGS1 2815/4885
US-11753384-B2 Production method for 5,5-di-substituted-4,5-dihydroisoxazole CYP3A5, CYP3A4, DHPS ALOX5 211/4885PTGS1 758/4885
US-20200369631-A1 METHOD FOR PRODUCING THIOCARBOXAMIDINE SALT COMPOUND TST, CBR3, NISCH ALOX5 673/4885PTGS1 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.