Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2256332 | 0.76 | TACR2 (0.45) | CRHR1 | |
| SCHEMBL16475240 | 0.65 | NNMT (0.43) | CRHR1NNMTPIK3CAPOLQ | |
| SCHEMBL2259585 | 0.65 | MAPT (0.31) | — | |
| SCHEMBL2255190 | 0.62 | NNMT (0.38) | CRHR1NNMTORAI1POLQCYP2A6 | |
| SCHEMBL20912237 | 0.62 | NNMT (0.43) | CRHR1NNMTCYP2A6 | |
| SCHEMBL2256730 | 0.62 | MAPT (0.48) | CRHR1 | |
| SCHEMBL2614474 | 0.61 | NNMT (0.55) | NNMTPIK3CAPOLQCYP2A6 | |
| SCHEMBL16475095 | 0.60 | NNMT (0.47) | NNMTORAI1CYP2A6 | |
| SCHEMBL5183305 | 0.59 | DGAT1 (0.49) | NNMTTSHRCYP2A6 | |
| SCHEMBL1423802 | 0.59 | LRRK2 (0.49) | CRHR1NNMTPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994203-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-08-09 | — | — | US | disclosed |
| US-20100035874-A1 | Organic compounds | NOVARTIS AG (CH) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035874-A1 | Organic compounds | CRH, CRHR1, CRHR2 | CRHR1 2/4885NNMT 3988/4885TSHR 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.