Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544597 | 0.81 | PTPN1 (0.51) | SRD5A2SRD5A1TTRHDAC1UNG | |
| SCHEMBL22553051 | 0.81 | NFE2L2 (0.67) | NFE2L2TTRHDAC1 | |
| SCHEMBL22553049 | 0.81 | NFE2L2 (0.67) | NFE2L2TTRHDAC1 | |
| SCHEMBL5693326 | 0.81 | MIF (0.59) | NFE2L2HTR2AHTR2CKCNH2TTR | |
| SCHEMBL8319110 | 0.81 | MIF (0.59) | NFE2L2HTR2AHTR2CKCNH2TTR | |
| SCHEMBL4319700 | 0.80 | KDM4E (0.48) | NFE2L2SRD5A2HTR2AHTR2CKCNH2 | |
| SCHEMBL4319695 | 0.80 | KDM4E (0.48) | NFE2L2SRD5A2HTR2AHTR2CKCNH2 | |
| SCHEMBL13535961 | 0.79 | HTT (0.50) | SRD5A2P4HBLMNAMAPK1HTT | |
| SCHEMBL8475379 | 0.78 | BCL2L1 (0.54) | NFE2L2SRD5A2SRD5A1TTRHDAC1 | |
| SCHEMBL16687611 | 0.78 | SRD5A1 (0.55) | SRD5A2SRD5A1TTRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961178-B2 | Cycloaddition reactions using quantum dots | NORTHWESTERN UNIVERSITY (US) | 2021-03-30 | — | — | US | disclosed |
| US-10961178-B2 | Cycloaddition reactions using quantum dots | NORTHWESTERN UNIVERSITY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200331836-A1 | CYCLOADDITION REACTIONS USING QUANTUM DOTS | NORTHWESTERN UNIVERSITY | 2020-10-22 | — | — | US | disclosed |
| US-20200331836-A1 | CYCLOADDITION REACTIONS USING QUANTUM DOTS | NORTHWESTERN UNIVERSITY | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331836-A1 | CYCLOADDITION REACTIONS USING QUANTUM DOTS | SYNGR2, SYNJ1, SQLE | NFE2L2 882/4885SRD5A2 3287/4885SRD5A1 3464/4885 |
| US-10961178-B2 | Cycloaddition reactions using quantum dots | SYNGR2, SYNJ1, SQLE | NFE2L2 882/4885SRD5A2 3287/4885SRD5A1 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.