SCHEMBL225532

SCHEMBL225532

CCOC(c1ccccc1)C(O[SiH3])(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
FFAR1 O14842 1/20 0.37
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
MMP8 P22894 1/20 0.33
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
KMT2A Q03164 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225533 0.82 POLB (0.40) L3MBTL1POLBTSHRMMP8LMNA
SCHEMBL4245934 0.79 L3MBTL1 (0.36) L3MBTL1FFAR1POLBTSHRMAPK1
SCHEMBL19356619 0.77 FFAR1 (0.34) L3MBTL1FFAR1POLBTSHRPPARG
SCHEMBL13677216 0.73 FFAR1 (0.44) L3MBTL1FFAR1POLBHPGDALOX15
SCHEMBL1685918 0.71 FFAR1 (0.46) L3MBTL1FFAR1POLBTSHRPPARG
SCHEMBL16343820 0.69 FFAR1 (0.33) FFAR1
SCHEMBL17311052 0.69 FFAR1 (0.53) L3MBTL1FFAR1POLBPPARGPPARA
SCHEMBL230733 0.68 KMT2A (0.33) KMT2A
SCHEMBL229913 0.68 THRB (0.33) LMNA
SCHEMBL18297933 0.67 L3MBTL1 (0.40) L3MBTL1POLBTSHRMAPK1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623958-B2 Oil-in-water silicone emulsion composition DOW CORNING TORAY CO. LTD. (JP) 2014-01-07 US disclosed
EP-2406323-B1 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO LTD (JP) 2013-07-24 EP disclosed
EP-2406322-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2406323-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004354-A1 Oil-In-Water Silicone Emulsion Composition DOW TORAY CO., LTD. (JP) 2012-01-05 US disclosed
US-20110319557-A1 Oil-In-Water Silicone Emulsion Composition DOW CORNING TORAY CO., LTD. (JP) 2011-12-29 US disclosed
WO-2010104186-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed
WO-2010104185-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed