SCHEMBL225533

SCHEMBL225533

CCOC(OCC)(OCC)C(O[SiH3])c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
MMP8 P22894 1/20 0.37
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225532 0.82 L3MBTL1 (0.38) POLBMMP8LMNAMEN1NPC1
SCHEMBL230734 0.80 KMT2A (0.35) KMT2AALDH1A1TSHR
SCHEMBL5570358 0.78 LMNA (0.38) POLBLMNAL3MBTL1
SCHEMBL705886 0.75 ATM (0.39) KMT2AL3MBTL1
SCHEMBL4245934 0.74 L3MBTL1 (0.36) POLBMMP8LMNAL3MBTL1TSHR
SCHEMBL10713851 0.71 TSHR (0.39) LMNAALDH1A1TSHR
SCHEMBL11802564 0.70 ALDH1A1 (0.35) LMNAL3MBTL1ALDH1A1
SCHEMBL29157994 0.69 MAPK1 (0.33) ALDH1A1TSHR
SCHEMBL18297933 0.68 L3MBTL1 (0.40) POLBMMP8LMNAL3MBTL1TSHR
SCHEMBL7074781 0.68 TAAR1 (0.39) POLBMMP8LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623958-B2 Oil-in-water silicone emulsion composition DOW CORNING TORAY CO. LTD. (JP) 2014-01-07 US disclosed
EP-2406323-B1 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO LTD (JP) 2013-07-24 EP disclosed
EP-2406322-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2406323-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004354-A1 Oil-In-Water Silicone Emulsion Composition DOW TORAY CO., LTD. (JP) 2012-01-05 US disclosed
US-20110319557-A1 Oil-In-Water Silicone Emulsion Composition DOW CORNING TORAY CO., LTD. (JP) 2011-12-29 US disclosed
WO-2010104186-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed
WO-2010104185-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed