Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530592 | 0.75 | BRD4 (0.40) | CREBBPBRD4AKR1B1MAPTSMN1; SMN2 | |
| SCHEMBL15667344 | 0.69 | TDP1 (0.57) | CREBBPBRD4AKR1B1MAPTSMN1; SMN2 | |
| SCHEMBL15667383 | 0.69 | TDP1 (0.57) | CREBBPBRD4AKR1B1MAPTSMN1; SMN2 | |
| SCHEMBL318360 | 0.69 | TDP1 (0.57) | CREBBPBRD4AKR1B1MAPTSMN1; SMN2 | |
| SCHEMBL8404573 | 0.69 | PTGS2 (0.40) | CREBBPBRD4AKR1B1PTGS2MAPT | |
| SCHEMBL8344689 | 0.68 | CA2 (0.49) | CREBBPBRD4AKR1B1MAPTALDH1A1 | |
| SCHEMBL10054037 | 0.68 | CREBBP (0.45) | CREBBPBRD4AKR1B1MAPTALDH1A1 | |
| SCHEMBL11926950 | 0.67 | CREBBP (0.44) | CREBBPBRD4AKR1B1MAPTTDP1 | |
| SCHEMBL18743290 | 0.67 | CREBBP (0.44) | CREBBPBRD4AKR1B1MAPTTDP1 | |
| SCHEMBL18643710 | 0.67 | CREBBP (0.44) | CREBBPBRD4AKR1B1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331904-A1 | 3-AMINO-[1,2,4]-TRIAZOLE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331904-A1 | 3-AMINO-[1,2,4]-TRIAZOLE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | NAT1, AGXT, CYP4Z1 | CREBBP 4300/4885BRD4 1058/4885AKR1B1 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.