Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.37 |
| ▸ | ANPEP | P15144 | 5/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556902 | 0.80 | MMP2 (0.38) | MMP2ANPEPCHRM4RIPK1SMYD3 | |
| SCHEMBL22556900 | 0.80 | MMP2 (0.38) | MMP2ANPEPCHRM4RIPK1SMYD3 | |
| SCHEMBL22556913 | 0.78 | LRRK2 (0.41) | GRM5 | |
| SCHEMBL22557386 | 0.75 | USP30 (0.48) | MMP2ANPEPSMYD3GRM5 | |
| SCHEMBL22556925 | 0.71 | GRM5 (0.40) | GRM5 | |
| SCHEMBL25308019 | 0.68 | AGPAT2 (0.39) | — | |
| SCHEMBL22557294 | 0.67 | MMP2 (0.41) | MMP2ANPEPCHRM4 | |
| SCHEMBL6521518 | 0.66 | MMP13 (0.42) | S1PR1 | |
| SCHEMBL23069407 | 0.66 | USP30 (0.42) | MMP2GRM5 | |
| SCHEMBL29158597 | 0.66 | USP30 (0.42) | MMP2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212351-A1 | SUBSTITUTED CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2020-10-22 | — | — | WO | disclosed |