Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556900 | 1.00 | MMP2 (0.38) | MMP2ANPEPRIPK1SMYD3CHRNA7 | |
| SCHEMBL22557643 | 0.80 | MMP2 (0.37) | MMP2ANPEPRIPK1SMYD3CHRM4 | |
| SCHEMBL22556925 | 0.79 | GRM5 (0.40) | ABL1USP30KCNJ1KCNH2 | |
| SCHEMBL22468535 | 0.75 | ABL1 (0.49) | SMYD3ABL1 | |
| SCHEMBL22557386 | 0.73 | USP30 (0.48) | MMP2ANPEPSMYD3USP30 | |
| SCHEMBL22556913 | 0.71 | LRRK2 (0.41) | USP30 | |
| SCHEMBL3954087 | 0.67 | CTSL (0.53) | MMP2 | |
| SCHEMBL25305510 | 0.67 | HDAC1 (0.50) | RIPK1KCNH2 | |
| SCHEMBL25258088 | 0.67 | HDAC1 (0.50) | RIPK1KCNH2 | |
| SCHEMBL28971352 | 0.67 | HDAC1 (0.50) | RIPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020212351-A1 | SUBSTITUTED CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2020-10-22 | — | — | WO | disclosed |