Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879473 | 0.82 | GRM2 (0.55) | GRM2SLC9A1TDP1TSHRGLA | |
| SCHEMBL21900390 | 0.77 | POLB (0.44) | POLBKDM4ELMNANPSR1TSHR | |
| SCHEMBL24266819 | 0.75 | KDM4E (0.52) | SLC9A1POLBKDM4ELMNANPSR1 | |
| SCHEMBL13896899 | 0.73 | KCNMA1 (0.61) | GRM2SLC9A1TDP1KDM4ELMNA | |
| SCHEMBL9305191 | 0.72 | GAA (0.66) | GRM2SLC9A1TDP1LMNATSHR | |
| SCHEMBL30368818 | 0.72 | GAA (0.66) | GRM2SLC9A1TDP1LMNATSHR | |
| SCHEMBL16879845 | 0.71 | CYP19A1 (0.60) | GRM2 | |
| SCHEMBL6946472 | 0.71 | TDP1 (0.68) | GRM2SLC9A1TDP1CYP2C9KCNMA1 | |
| SCHEMBL2734889 | 0.70 | GRM2 (1.00) | GRM2SLC9A1TDP1KDM4EMAPT | |
| SCHEMBL14102741 | 0.69 | SLC9A1 (0.50) | GRM2SLC9A1TDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089966-B1 | NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE | ESTRYX PHARMA LTD (GB) | 2020-10-21 | — | — | EP | disclosed |