Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13896899 | 0.77 | KCNMA1 (0.61) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL16879473 | 0.71 | GRM2 (0.55) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL30360007 | 0.70 | TSHR (0.70) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL285179 | 0.70 | TSHR (0.70) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL22561764 | 0.69 | GRM2 (0.52) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL2734889 | 0.68 | GRM2 (1.00) | SLC9A1GRM2TDP1KCNMA1ALDH1A1 | |
| SCHEMBL1774497 | 0.67 | SLC9A1 (0.70) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL31234269 | 0.67 | SLC9A1 (0.70) | SLC9A1TSHRGRM2GLATDP1 | |
| SCHEMBL15078635 | 0.65 | TSHR (0.82) | SLC9A1TSHRGRM2GLAHPGD | |
| SCHEMBL27890018 | 0.64 | RPS6KA3 (0.68) | SLC9A1TSHRGRM2GLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020445-B1 | FUSED PYRIDINE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |