Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561764 | 0.77 | GRM2 (0.52) | POLBTSHRNPSR1KDM4ELMNA | |
| SCHEMBL28474799 | 0.69 | CALM1 (0.44) | KDM4ELMNAKMT2AMAPTMEN1 | |
| SCHEMBL16879473 | 0.69 | GRM2 (0.55) | TSHRKCNMA1PTK2GLA | |
| SCHEMBL24266819 | 0.69 | KDM4E (0.52) | POLBTSHRNPSR1KDM4ELMNA | |
| SCHEMBL16491892 | 0.64 | KCNMA1 (0.64) | POLBTSHRNPSR1KDM4ELMNA | |
| SCHEMBL19410282 | 0.63 | KCNMA1 (0.59) | POLBTSHRNPSR1KDM4ELMNA | |
| SCHEMBL26227380 | 0.63 | MAPT (0.51) | POLBTSHRNPSR1KDM4ELMNA | |
| SCHEMBL16382186 | 0.63 | IDO1 (0.43) | TSHRNPSR1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9996132 | 0.63 | KCNMA1 (0.42) | POLBTSHRNPSR1KDM4ELMNA | |
| SCHEMBL24516995 | 0.63 | POLB (0.50) | POLBTSHRNPSR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081829-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-04-23 | — | — | WO | disclosed |