Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591917 | 0.81 | ALDH1A1 (0.40) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL23475236 | 0.79 | GAA (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL3901383 | 0.75 | MAPT (0.36) | BCL2MCL1ALDH1A1HPGDMAPT | |
| SCHEMBL21101742 | 0.74 | ALDH1A1 (0.33) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21102094 | 0.74 | HTT (0.34) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL5382681 | 0.71 | CYP3A4 (0.37) | LMNABCL2MCL1HTTALDH1A1 | |
| SCHEMBL4322937 | 0.71 | GABRA1 (0.46) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30583122 | 0.71 | GABRA1 (0.46) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL22056338 | 0.69 | THRB (0.35) | LMNABCL2MCL1HPGDSMN1; SMN2 | |
| SCHEMBL598624 | 0.69 | LMNA (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286261-B1 | POROUS CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING SAME | UNIV CORNELL (US) | 2020-10-21 | — | — | EP | disclosed |