SCHEMBL2256245

SCHEMBL2256245

[c]1ccc2ccc(-c3ccccc3)cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.50
ESR2 Q92731 6/20 0.50
BACE1 P56817 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
PGR P06401 1/20 0.41
NPC1 O15118 1/20 0.40
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
ALOX5 P09917 2/20 0.38
FGFR1 P11362 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
DYRK3 O43781 1/20 0.38
CLK1 P49759 1/20 0.38
CLK2 P49760 1/20 0.38
CLK3 P49761 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256257 0.92 ESR1 (0.48) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL2251915 0.92 ESR1 (0.48) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL148071 0.92 ESR1 (0.52) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL2446899 0.92 ESR1 (0.52) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL2274784 0.90 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2NPC1
SCHEMBL2453077 0.89 ESR1 (0.48) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL2447055 0.89 ESR1 (0.48) ESR1ESR2BACE1HSD17B1HSD17B2
SCHEMBL11898490 0.86 ESR1 (0.47) ESR1ESR2HSD17B1HSD17B2NPC1
SCHEMBL2271000 0.86 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2NPC1
SCHEMBL8591440 0.83 ESR1 (0.59) ESR1ESR2BACE1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337532-A1 TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE TOSOH CORPORATION (JP) 2023-10-19 US claimed
CN-116348454-A Triazine compound, material for organic electroluminescent element, electron-transporting material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2023-06-27 CN claimed
WO-2022075219-A1 TRIAZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2022-04-14 WO claimed
CN-106632356-A Benzodiazepine derivative, preparation method of benzodiazepine derivative and organic light emitting diode 上海升翕光电科技有限公司 2017-05-10 CN claimed
US-20230337532-A1 TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE TOSOH CORPORATION (JP) 2023-10-19 US disclosed
CN-116348454-A Triazine compound, material for organic electroluminescent element, electron-transporting material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2023-06-27 CN disclosed
WO-2022075219-A1 TRIAZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2022-04-14 WO disclosed
US-11072573-B2 Binaphthyl compounds REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2021-07-27 US disclosed
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
CN-112119514-A Organic light emitting device 株式会社LG化学 2020-12-22 CN disclosed
US-20200354299-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2020-11-12 US disclosed
EP-1916244-A1 THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2008-04-30 EP disclosed
EP-1882694-A1 THIOPHENE COMPOUND HAVING PHOSPHORIC ESTER AND PROCESS FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2008-01-30 EP disclosed
US-20070208053-A1 Fused heterobicyclic kinase inhibitors OSI PHARMACEUTICALS, INC. 2007-09-06 US disclosed
WO-2007084667-A2 FUSED HETEROBICYCLIC KINASE INHIBITORS OSI PHARMACEUTICAL, INC. (US) 2007-07-26 WO disclosed
US-20070149521-A1 Bicyclic protein kinase inhibitors OSI PHARMACEUTICALS, INC. 2007-06-28 US disclosed
WO-2007064993-A2 BICYCLIC PROTEIN KINASE INHIBITORS OSI PHARMACEUTICALS, INC. (US) 2007-06-07 WO disclosed
US-4061617-A ANTIOXIDANT, DIELECTRIC STABILIZERS, SEMICONDUCTORS, ION EXCHANGE RESINS GENERAL ELECTRIC COMPANY (US) 1977-12-06 US disclosed
US-3959223-A Oxidation-reduction diphenoquinone-diphenonhydroquinone polymers GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354299-A1 BINAPHTHYL COMPOUNDS UACA, C9, C1S ESR1 1934/4885ESR2 1711/4885BACE1 3029/4885
US-20070149521-A1 Bicyclic protein kinase inhibitors CDK1, MAP4K2, MAP4K3 ESR1 2277/4885ESR2 3281/4885BACE1 1025/4885
US-11072573-B2 Binaphthyl compounds UACA, C9, C1S ESR1 1934/4885ESR2 1711/4885BACE1 3029/4885
US-20230337532-A1 TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE ARNT, TPH1, AHR ESR1 423/4885ESR2 174/4885BACE1 2851/4885
US-20070208053-A1 Fused heterobicyclic kinase inhibitors MAP2K5, MAP2K7, MAP2K2 ESR1 853/4885ESR2 911/4885BACE1 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.