Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.57 |
| ▸ | FEN1 | P39748 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278113 | 0.89 | ALDH1A1 (0.61) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL7390637 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL641759 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL29859075 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL2211446 | 0.83 | ALDH1A1 (0.67) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL11755601 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL27439105 | 0.82 | ABL1 (0.51) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL481408 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL2125979 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL4516558 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPK1HIF1AERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994203-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-08-09 | — | — | US | disclosed |
| US-20100035874-A1 | Organic compounds | NOVARTIS AG (CH) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035874-A1 | Organic compounds | CRH, CRHR1, CRHR2 | ALDH1A1 1728/4885MAPK1 913/4885HIF1A 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.