Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564534 | 0.89 | LMNA (0.39) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22564307 | 0.89 | NPC1 (0.36) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22563971 | 0.89 | MAPT (0.40) | HTTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL22564474 | 0.89 | HTT (0.40) | HTTAPEX1NPC1RAB9ANR1H4 | |
| SCHEMBL22564338 | 0.89 | CTSD (0.35) | HTTNPC1RAB9ANR1H4SMN1; SMN2 | |
| SCHEMBL22564283 | 0.87 | NR1H4 (0.38) | APEX1NR1H4KDM4EALDH1A1LMNA | |
| SCHEMBL22564542 | 0.87 | NPC1 (0.37) | HTTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22564309 | 0.87 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL22564009 | 0.87 | APEX1 (0.34) | HTTAPEX1NPC1FABP4NR1H4 | |
| SCHEMBL18504650 | 0.87 | HTT (0.40) | HTTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |